lyonization - перевод на русский
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lyonization - перевод на русский

INACTIVATION OF COPIES OF X CHROMOSOME
Lyon hypothesis; X inactivation; Lyonization; Lionisation; X chromosome inactivation; Lyon effect; Lyonisation; X-inactivations; Lyon Hypothesis; X-chromosome inactivation; Random X-inactivation; XCI; Lyon principle; Mammalian X-inactivation
  • The process and possible outcomes of random X-[[chromosome]] inactivation in female human embryonic cells undergoing [[mitosis]]. <br>
1.Early stage embryonic cell of a female human <br>
2.Maternal X chromosome <br>
3.Paternal X chromosome <br>
4.Mitosis and random X-chromosome inactivation event <br>
5.Paternal chromosome is randomly inactivated in one daughter cell, maternal chromosome is inactivated in the other <br>
6.Paternal chromosome is randomly inactivated in both daughter cells <br>
7.Maternal chromosome is randomly inactivated in both daughter cells <br>
8.Three possible random combination outcomes

lyonization         

общая лексика

лайонизация (инактивация и гетерохроматинизация одной из X-хромосом самки в эмбриогенезе)

Википедия

X-inactivation

X-inactivation (also called Lyonization, after English geneticist Mary Lyon) is a process by which one of the copies of the X chromosome is inactivated in therian female mammals. The inactive X chromosome is silenced by being packaged into a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation).

The choice of which X chromosome will be inactivated in a particular embryonic cell is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism (its cell line). The result is that the choice of inactivated X chromosome in all the cells of the organism is a random distribution, often with about half the cells having the paternal X chromosome inactivated and half with an inactivated maternal X chromosome; but commonly, X-inactivation is unevenly distributed across the cell lines within one organism (skewed X-inactivation).

Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally-derived X chromosome.

Как переводится lyonization на Русский язык